Epitalon Research Reference
A documentation-focused reference page for Epitalon (also spelled Epithalon) as a research compound. It covers what the material is, its research context, how purity and identity are verified, and how it is stored and handled in the lab. No effects are claimed. Supplied for research use only.
What it is
Epitalon is a synthetic tetrapeptide with the amino acid sequence Ala-Glu-Asp-Gly (AEDG). It has a molecular formula of C14H22N4O9 and a molecular weight of approximately 390.35 g/mol. It is produced by controlled solid-phase peptide synthesis and supplied as a lyophilized powder for stability during storage and handling.
Research context
Epitalon is characterized in laboratory research examining telomere biology, gene-expression regulation, and pineal-linked signaling pathways. This page notes the research areas in which the tetrapeptide is referenced; it makes no claim about any effect. A purity-verified reference material is useful in these contexts because it provides a defined, characterized compound for study.
How purity is verified
The material is characterized per lot using the standard analytical stack:
- HPLC for purity, read with the chromatogram; research-grade material is ≥99% by HPLC.
- Mass spectrometry for identity, matching the observed mass to the theoretical mass for the AEDG sequence.
- LAL (Limulus Amebocyte Lysate) for bacterial endotoxin, commonly referenced to USP <85>.
All three results are documented on a lot-matched certificate tied to the lot number on the vial. Material is synthesized in the USA.
Storage and handling for lab use
General laboratory handling notes for lyophilized Epitalon:
- Lyophilized powder. Commonly referenced as stable at room temperature for a short window (on the order of a few weeks) under desiccated conditions, with storage below about -18°C in desiccated conditions for extended periods.
- Keep sealed and dry. Store desiccated and keep the vial sealed until ready to weigh and reconstitute.
- Reconstitution. Reconstitute with an appropriate solvent (bacteriostatic water is commonly referenced), adding slowly along the vial wall and swirling gently.
- Reconstituted solution. Commonly stored at 2-8°C and used within a working window of roughly 1-4 weeks depending on handling and vehicle. Avoid repeated freeze-thaw cycles.
Exact parameters depend on your protocol and the requirements of the work.
Documentation summary
Epitalon reference material at Stacy & Chad is verified ≥99% by HPLC, confirmed by mass spectrometry, screened for endotoxin by LAL, synthesized in the USA, and shipped with a lot-matched certificate you can read before purchase. Supplied strictly for research use only.
Every lot ships with its own published COA.
Third-party HPLC purity, endotoxin screened, made in the USA — the certificate is on the product page before you buy. Buy 2, Get 1 Free + free shipping.
See the catalog →Frequently asked questions
What is Epitalon?
Epitalon (Epithalon) is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly (AEDG), molecular formula C14H22N4O9 and molecular weight around 390.35 g/mol. It is supplied as a lyophilized powder for research use.
Is Epitalon the same as Epithalon?
Yes. "Epitalon" and "Epithalon" are two spellings of the same synthetic AEDG tetrapeptide.
How is Epitalon purity verified?
Per lot, using HPLC for purity (≥99% research-grade), mass spectrometry for identity against the AEDG sequence, and the LAL assay for endotoxin, all documented on a lot-matched certificate of analysis.
How should Epitalon be stored?
As a lyophilized powder it is commonly kept desiccated, with short-term room-temperature stability on the order of weeks and storage below about -18°C for extended periods. Reconstituted solution is typically refrigerated at 2-8°C with freeze-thaw cycles avoided.
Is research Epitalon for human use?
No. It is supplied for research use only, as a characterized laboratory reference compound, not for human, veterinary, or diagnostic use. ## Related pages - Browse research compounds - How to read a peptide COA - See our published lot-matched COAs